2022
	Yes
	https://www.mdpi.com/1660-4601/19/8/4580
	Isa, Khairul Nizam Mohd
	Asia
	Epidemiology Study
	Students
	Middle/Jr High (6-8)
	Carbon Dioxide (CO2)
	Particulate Matter (PM)
	Temperature
	Humidity
	Fungi
	Respiratory symptoms
	Feno
	School children
	Urban
	suburban
	indoor pollutants
	We found that the median of FeNO in the school children from urban areas (22.0 ppb, IQR = 32.0) were slightly higher as compared to the suburban group (19.5 ppb, IQR = 24.0). After adjustment of potential confounders, the two-level hierarchical multiple logistic regression models showed that the concentrations of PM2.5 were significantly associated with elevated of FeNO (>20 ppb) in school children from suburban (OR = 1.42, 95% CI = 1.17-1.72) and urban (OR = 1.30, 95% CI = 1.10-1.91) areas. Despite the concentrations of NO2 being below the local and international recommendation guidelines, NO2 was found to be significantly associated with the elevated FeNO levels among school children from suburban areas (OR = 1.11, 95% CI = 1.06-1.17). The findings of this study support the evidence of indoor pollutants in the school micro-environment associated with FeNO levels among school children from suburban and urban areas.