2022 Yes https://onlinelibrary.wiley.com/doi/full/10.1111/ina.13116 Brink HW Europe Observational Students Temperature Humidity Carbon Dioxide (CO2) Particulate Matter (PM) Volatile Organic Compounds (VOCs) Test Performance Cognative function Performance Classrooms' indoor environmental quality Health Higher education Student responses Quality of learning During the pilot study, the IEQ of the classrooms varied slightly. Significant associations (p < 0.05) were observed between these natural variations and students' perceptions of the thermal environment and indoor air quality. These perceptions were significantly associated with their physiological and cognitive responses (p < 0.05). Furthermore, students' perceived cognitive responses were associated with their short-term academic performance (p < 0.01). The observed associations confirm the construct validity of the systematic approach.